Metastatic breast cancer also called stage IV or advanced breast cancer is not a specific type of breast cancer. It's the most advanced stage of breast cancer. Metastatic breast cancer is breast cancer that has spread beyond the breast and nearby lymph nodes to other organs in the body most often the bones, lungs, liver or brain.
This is an exciting time in metastatic breast cancer research. Many new treatments for metastatic breast cancer are under study and treatment is improving. Findings from clinical trials will determine whether or not new treatments will become a part of standard care for metastatic breast cancer.
Most women with stage IV breast cancer are treated with systemic therapy. This may include hormone therapy, chemotherapy, targeted therapy, or some combination of these. Local treatments such as surgery or radiation might also be used to help prevent or treat symptoms.
By Sam Wong. A woman with advanced breast cancer has made a dramatic recovery after receiving a personalised therapy using her own immune cells. A year later, they had disappeared.
Metastatic breast cancer also called stage IV is breast cancer that has spread to another part of the body, most commonly the liver, brain, bones, or lungs. Cancer cells can break away from the original tumor in the breast and travel to other parts of the body through the bloodstream or the lymphatic system, which is a large network of nodes and vessels that works to remove bacteria, viruses, and cellular waste products. Breast cancer can come back in another part of the body months or years after the original diagnosis and treatment. A metastatic tumor in a different part of the body is made up of cells from the breast cancer.
Skip to Content. Use the menu to see other pages. Doctors are working to learn more about metastatic breast cancer, including ways to prevent it, how to best treat it, and how to provide the best care to people diagnosed with this disease.
Those long-lasting remissions are reported after locoregional treatment of the primary tumor and all metastatic sites in several case series; however, unlike other tumor entities, prospective data are lacking. Furthermore, tumor eradication by excellent systemic anticancer therapy with novel chemotherapies and targeted agents can lead to long-term survival. In addition, reactivation of the host immune defense by immuno-oncologic drugs can achieve long-lasting tumor control. This short review summarizes available data on long-lasting remissions and potential cure in metastatic breast cancers.